Health: Sickle Cell Disease

  • What is it? – It is an inherited blood disorder.
  • Effect
    • It affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body.
    • People with this disease have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
  • What causes it? – The cause of Sickle cell disease is a defective gene, called a sickle cell gene.
  • Symptoms:
    • Early stage: Extreme tiredness or fussiness from anemia, painfully swollen hands and feet, and jaundice.
    • Later stage: Severe pain, anemia, organ damage, and infections.
  • Treatments – The only cure for this disease is bone marrow or stem cell transplantation.

 

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